CCBRC Workshop: Protein Structure Prediction and Glycosylation

November 10, 2022, 9:00 a.m. - 12:00 p.m.

The Computational Chemistry and Bioinformatics Research Core (CCBRC) of GlyCORE is pleased to announce registration is open for the free Hands-on Computational Glycoscience Workshop, "Protein Structure Prediction and Glycosylation,"  with hands-on software training in Modeller, AlphaFold, and Charmm-GUI, scheduled for Thursday, November 10, 2022, from 9:00 a.m.to 12:00 p.m. CDT, in classroom 106 E, J. D. Williams Library, University of Mississippi.

Accessing the dynamic three-dimensional structure of a protein can give tremendous insight into how the protein functions, and helps us to plan how we could control or modify its functions. Knowledge of a protein’s structure opens a door to an understanding of how a ligand (small molecule, glycan, DNA/RNA) can bind to the protein and have a significant impact on the protein’s conformation, folding, stability, and activity. During the workshop, participants will learn the basics of protein structure as well as protein folding; do hands-on protein structure prediction (using MODELLER and AlphaFold), and use Charmm-GUI/Glycam-Web to build a fully glycosylated model of a protein. Participants can do the hands-on exercise on their own problem and the instructor(s) will help you in getting started with the structure prediction and any required troubleshooting. Graduate students with no computational background are highly encouraged to join the workshop and learn some new skills.

  • Registration is free, but required at the following link: November 10, 2022 Computational Glycoscience Workshop
  • Early registration is encouraged as space is limited
  • Registration closes 11/07/2022 at 5 p.m. CT
  • One participant will receive free access to a $350 online course by Schrodinger

Decorative image of workshop flyer