Education:
- Ph.D. University of Hawaii
- B.S. Bemidji State University
Appointment(s):
- Professor of Pharmacognosy
- Research Professor in the Research Institute of Pharmaceuitcal Sciences
- Professor of Chemistry and Biochemistry
- Professor of Pharmacology
Career Highlights:
B.S. degree in Chemistry and Biology from Bemidji State University in Bemidji, Minnesota in 1985.
Chemist for Reid-Rowell labs (Solvay Pharmaceuticals) in Baudette Minnesota from 1985-1988.
Ph. D. in Marine Natural Products Chemistry under the direction of the Late Professor Emeritus Paul J. Scheuer at the Department of Chemistry of the University of Hawaii, Manoa in 1992.
Honors and Awards
Section Editor of Biochimica and Biophysica et Acta 2006-
Guest Editor of Molecules Special Issue “Antiinfective Agents” 2009-2010
Member of The Journal of Natural Products Editorial Board
Member of Editorial Board for Botanics: Targets and Therapy.
Author of a new and controversial finding selected by the Faculty of 1000 Biology Reports 2010
Author of the top download paper of the year 2005 (awarded in 2006) in Comparative Biochemistry and Physiology
Member of the NIH Synthetic and Biological Chemistry Study Section 2010-
Ad Hoc Member of the NIH AIDS Special Emphasis Panel (ZRG1 AARR-E) 2007-2009
Ad Hoc Member of the Florida Sea Grant Marine Biotechnology and Sustainable Production Panel 2007
Chair of an NIH Ad Hoc and Experimental Electronic Review Section for NIH F32 Fellowships Applications (ZRG1 AARR-D22L) AIDS Fellowships 2006
Member of the NIH AIDS Discovery and Development of Therapeutics (ADDT) Study Section 2003-2006
Scientific Program Committee for the International Meeting on Marine Biotechnology 2004
Interests:
Dr. Hamann’s research group explores the NMR structure, synthesis, pharmacology, ecological roles and pharmaceutical utility of marine natural products. Dr Hamann’s group also explores the role of bacterial symbiosis on the production of clinically significant natural products.
Click Here to View Current Research and PublicationsDr. Hamann’s research group is actively involved in the isolation, structure assignment using NMR and synthesis of marine natural products with activity against cancer, malaria, tuberculosis and neurological disorders. Metabolites are isolated from a variety of sources including marine invertebrates, algae, bacteria and dinoflagellates. In addition to drug leads Dr. Hamann’s group is involved in the characterization of molecules associated with harmful algal blooms and the role of symbiosis on the production of invertebrate secondary metabolites. NMR structure assignments are made utilizing two dimensional methods to assign gross, relative and absolute configuration. Molecular modeling is utilized extensively to assist with and validate NMR assignments and a combination of chemical and spectroscopic methods are utilized to solve relative and absolute configuration. A combination of synthesis and biosynthesis are utilized together to assemble and optimize complex, biologically active marine natural products. Some of the classes of marine natural products characterized can be generated effectively utilizing total synthesis however for many classes a combination of biosynthesis and chemical synthesis are essential to generate a product cost-effectively.
Search Dr. Hamann‘s publications