Patents & Publications

Google Scholar Link

PubMed Link


  1. Joshi VM, Mandaogade PM, Chougule MB, Jain GK, International Patent, pharmaceutical compositions of bupropion, WO/2008/026044, 2008
  2. Joshi VM, Mandaogade PM, Chougule MB, Jain GK, International Patent, Stable pharmaceutical compositions of bupropion, WO/2008/129465, 2008
  3. Joshi VM, Mandaogade PM, Chougule MB, Jain GK, pharmaceutical composition comprising bupropion or salt thereof and stabilizer, Indian patent, 771/MUM/2007 A, 2007
  4. Mandaogade PM, Joshi VM, Chougule MB, Srivastav S., Jain GK, , G. K. Jain, Stabilized pharmaceutical composition of bupropion or salt thereof, Indian patent, 1389/MUM/2006 A, 2006
  5. Joshi VM, Chougule MB, Mandaogade PM Jain GK,, Melt-granulated bupropion sustained release formulation, Indian patent, 1375/MUM/2006 A, 2006
  6. Misra A, Chougule MB, Ganesh S., and Padhi B, Indian patent, Aerodynamically light porous dry powder inhaler formulations for targeted pulmonary deposition (2006 no. 953/MUM/2006
  7. Misra A, Chougule MB, Padhi B, Ganesh S. Indian patent, Enhancement of pulmonary therapeutic index of drugs from dry powder inhaler formulations, 729/ MUM /2005
  8. Misra A, Chougule M, Padhi B, Indian patent, Engineered monodisperse inhalation powders for effective treatment of lung diseases, 228/MUM/2005
  9. Chougule MB, Bachmann AS, Development of ligand-mediated nanocarrier system of DFMO alone and/or in combination with chemotherapeutic drug for the treatment of cancer, U.S. provisional application No. 61/558,368

Selected Publications

  1. España-Serrano L and Chougule MB*. Enhanced anticancer activity of PF-04691502, a dual PI3K/mTOR inhibitor, in combination with VEGF siRNA against non-small cell lung cancer. Molecular Therapy – Nucleic Acids, (Nature publishing group), 2016 Nov 5;5(11):e384.
  2. Youngren-Ortiz SR, Gandhi NS, España-Serrano L, Chougule MB*. Aerosol Delivery of siRNA to the Lungs. Part 1: Rationale for Gene Delivery Systems. Kona: powder science and technology in Japan. 2016;33:63.
  3. Tekade RK, Youngren-Ortiz SR, Yang H, Haware R, Chougule MB*. Albumin-chitosan hybrid onconase nanocarriers for mesothelioma therapy. Cancer Research. 2015;75(15 Supplement):3680.
  4. Glasgow MD, Chougule MB*. Recent developments in active tumor targeted multifunctional nanoparticles for combination chemotherapy in cancer treatment and imaging. Journal of biomedical nanotechnology. 2015;11(11):1859-98.
  5. Chougule MB, Tan C. Translational Application of Nano Delivery Systems: Emerging Cancer Therapy. AAPS PharmSciTech. 2015;16(1):3.
  6. Gandhi NS, Tekade RK, Chougule MB*. Nanocarrier mediated Delivery of siRNA/miRNA in Combination with Chemotherapeutic Agents for Cancer Therapy: Current Progress and Advances. Journal of Controlled Release. 2014; 194:238-56.
  7. Tekade RK, Youngren-Ortiz SR, Yang H, Haware R, Chougule MB*. Designing Hybrid Onconase NCs for Mesothelioma Therapy: A Taguchi Orthogonal Array and Multivariate Component Driven Analysis. Molecular Pharmaceutics. 2014; 11(10):3671-83.
  8. Chougule MB*, Patel AR, Patlolla R, Jackson T, Singh M*. Epithelial transport of Noscapine across cell monolayer and influence of absorption enhancers on in vitro permeation and bioavailability: implications for intestinal absorption. Journal of drug targeting. 2014; 22(6):1-11.
  9. Patel AR, Chougule MB, Lim E, Francis FP, Safe S, and Singh M*, Theranostic tumor homing NCs for the treatment of lung cancer. Nanomedicine. 2014; 10(5):1053-63.
  10. Youngren SR, Tekade RK, Gustilo B, Hoffmann PR, and Chougule MB*, STAT6 siRNA matrix-loaded gelatin NCs: formulation, characterization, and ex vivo proof of concept using adenocarcinoma cells. BioMed Research International. 2013; 2013:858946.
  11. Patel AR, Chougule MB, Townley I, Patlolla R, Wang G, Singh M*. Efficacy of aerosolized celecoxib encapsulated nanostructured lipid carrier in non-small cell lung cancer in combination with docetaxel. PHARM RES. 2013; 30(5):1435-46.
  12. Tekade, R.K. and Chougule MB*, Formulation development and evaluation of hybrid NC for cancer therapy: Taguchi orthogonal array based design. Biomed Res Int, 2013. 2013:712678.
  13. Chougule MB*, Tekade RK, Current Scene and Prospective Potentials of siRNA in Cancer Therapy. Journal of Pharmacogenom Pharmacoproteomics. 2012; 3:e125.
  14. Chougule MB, Patel AR, Sachdeva P, Jackson T, Singh M*. Anti-cancer activity of noscapine, an opioid alkaloid in combination with cisplatin in human non-small cell lung cancer. Lung Cancer, 2011, 71(3):271-82.
  15. Chougule MB, Patel AR, Jackson T, Singh M*. Antitumor activity of noscapine in combination with Doxorubicin in triple negative breast cancer. PLoS One. 2011; 6(3):e17733.
  16. Ichite N, Chougule MB, Patel AR, Jackson T, Safe S, Singh M*. Inhalation delivery of a novel diindolylmethane derivative for the treatment of lung cancer. Molecular Cancer Therapeutics. 2010; 9(11):3003-14. The first two authors contributed equally.
  17. Patlolla R, Chougule MB, Patel AR, Jackson T, and Singh M*. Celecoxib encapsulated nanostructured lipid carrier system for pulmonary delivery. Journal of Controlled Release. 2010; 144(2):233-41.