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The Glycobiology of Cancer

September 16, 2021 @ 12:00 pm - September 17, 2021 @ 4:00 pm CDT


The Glycobiology of Cancer Symposium (day 1)


Session I: Cancer Progression & Metastasis

Chair, Dr.  Karl Krueger, Program Director, NCI  

1:00p.m., Dr. Gerard C. Blobe, Duke University Medical School

Loss of ALK4 Function Promotes Cancer Progression Through Reprogramming of Receptor Glycosylation

1:30p.m., Dr. Kevin Yarema, Johns Hopkins Medical School  

Metabolic Glycoengineering Labeling of Sialic Acid for Early Cancer Detection

2:00p.m., Dr. Prakash Radhakrishnan, University of Nebraska Medical Center

Cancer-associated Short O-glycans in Pancreatic Cancer Malignancy

2:30p.m., Dr. Charles Dimitroff, Florida International University

The Role of Hypoxia Driving Melanoma Glycobiology Signature

3:00p.m., Break


Session II: Diagnostics & Therapeutics

Chair, Dr. Neeraja Sathyamoorthy, Program Director, NCI

3:15p.m., Dr. Joseph Contessa, Yale University Medical School                                                                                          

Developing an Inhibitor of N-glycosylation for Cancer Therapy                                                                             

3:45p.m., Dr. Steven Banik, Stanford University  

Targeted Protein Degradation from the Extracellular Space

4:00p.m., Dr. Mia L. Huang, Scripps Department of Molecular Medicine

Tools to Discover and Surveil Glycoconjugate Targets in Cancer Biology

4:15p.m., Dr. Dannielle Engle, Salk Institute for Biological Studies   

Interception of the Aberrant Glycan CA19-9 in Pancreatic Disease                                                                     

4:30p.m., Dr. Edgar Engleman, Stanford University School of Medicine

Targeting Dectin-2 for Tumor Immunotherapy

5:00p.m., Adjourn

The Glycobiology of Cancer Symposium (day 2)

Session III. Cell Signaling

Chair, Dr. Neeraja Sathyamoorthy, Program Director, NCI

1:00p.m., Dr. Mauricio Reginato, Drexel University

O-GlcNAcylation: Linking Signaling and Metabolism in Cancer

1:30p.m., Dr. Virginia Shapiro, Mayo Rochester

ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses

2:00p.m, Dr. Anita Hjelmeland, University of Alabama Birmingham

A Protumorigenic Role for ST6Gal1-Mediated Sialylation in Brain Tumor Initiating Cells

2:30p.m., Dr. Thomas Clausen, University of California San Diego                                                                         

Binding of Malarial VAR2CSA to Oncofetal Chondroitin Sulfate Depends on Sulfation and Ligand Accessibility                                                                                                                                                                            

3:00p.m., Break

Session IV. Glycoproteomics & Informatics

Chair, Dr. Karl Krueger, Program Director, NCI

3:15p.m., Dr. Richard Drake, Medical University of South Carolina

Integrated Workflows for Carbohydrate Antigen Immunohistochemistry, N-glycan Imaging Mass Spectrometry and Targeted Glycoproteomics on the Same Tumor Tissue Slide

3:45p.m., Dr. Stacy Malaker, Yale University                                                                                                                  

Revealing the Cancer-Associated Mucinome                                                                                                             

4:00p.m., Dr. Hui Zhang, Johns Hopkins School of Medicine

Characterization of Human Cancers by Glycoproteomics

4:30p.m., Dr. Raja Mazumder, Georgetown University  

Exploring Cancer Mutations and its Effect on Glycosylation Sites Using GlyGen Supersearch

4:45p.m., Dr. Lingjun Li, University of Wisconsin 

Development and Application of Chemical Tags for Quantitative Glycomics and Glycoproteomics                    

5:15p.m., Adjourn


September 16, 2021 @ 12:00 pm EDT
September 17, 2021 @ 4:00 pm EDT


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