Research Projects Archive 9.4.2018

Project Investigators

The Center of Research Excellence in Natural Products Neuroscience (CORE-NPN) supports a formal mentoring program to promote the establishment of independent research programs for investigators. All investigators receive bridge funding ($50,000 per year for maximum two years) to support their research. The investigators are required to submit a competitive R01 grant application to NIH within two years of receiving support through this program.

Publications

Each publication, press release, or other document supported by this award must include an acknowledgment of NIH award support such as “Research reported in this publication was supported by the National Institute Of General Medical Sciences of the National Institutes of Health under Award Number P30GM122733. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.” 

Prior to issuing a press release concerning any research outcome, please notify the PI of the award, Dr. Soumyajit Majumdar, who will contact the Program Officer and NIGMS for necessary coordination. He can be contacted at majumso@olemiss.edu or (662) 815-7828

For more information, refer to the NIH webpage here

Pilot Project Program

Request for Application

CORE-NPN Investigators

PROJECT 5: Delta-8-Tetrahydrocannabinol in the Management of Glaucoma
2012-present

P.I.: Michael Repka, Chair and Professor, Department of Pharmaceutics and Drug Delivery, Director of Pii Center for Pharmaceutical Technology.

The purpose of this project is to investigate how THC can be used and delivered in ocular tissues and assist in the management of Glaucoma.

PROJECT 6: Fluorinated Derivatives of Anthocyanin Natural Products for Brain Neurodegeneration
2015-present

P.I.: David Colby, Associate Professor, Department of BioMolecular Sciences

PROJECT 7: Intranasal Delivery of Ziconotide Using Muco-similar Vehicles
2015-present

Mentor: Michael Repka, Ph.D. P.I.: S. Narasimha Murthy, Associate Professor, Department of Pharmaceutics and Drug Delivery

Small Grant Projects

The goal of Small Grant Projects is to provide a mechanism that will allow rapid transition of investigators and their approved projects as COBRE-sponsored junior investigators. Since COBRE funds cannot be carried over from year-to-year, it is important to have junior investigators and projects waiting in the wings for rapid transition into fully-funded junior investigator slots as they become available (e.g. when an existing junior investigator project is funded as an independent R01). Therefore, the CORE-NPN supports Small Grants to junior faculty who conduct research at the interface of natural products and neuroscience.

Current Small Grant Recipients:

Kristie Willett

Project: Identifying Novel Cannabinoid Analogues for the Treatment of Dravet Syndrome

2016-present

P.I.: Kristine Willett
Professor, Department of BioMolecular Sciences

Joshua Sharp1

Project: In vitro Ligand Screening by Small Molecule Hydroxyl Radical Footprinting

2016-present

P.I.: Joshua Sharp
Associate Professor, Department of BioMolecular Sciences