- Ph.D. Oregon State University
- B.S.Ph. Oregon State University
- Professor of Pharmacognosy
- Research Professor in the Research Institute of Pharmaceutical Sciences
Dr. Nagle’s research focuses on the discovery of new drugs. His program combines natural products chemistry with cutting edge molecular mechanism-targeted bioassay techniques. Dr. Nagle explores the biomedical potential of natural products as new sources of drug leads for the treatment of cancer. He and Dr. Yu-Dong Zhou (National Center for Natural Products Research) have developed new molecular-based bioassays to investigate natural products for their potential to supplement existing chemotherapeutic agents by acting as promoters of tumor differentiation and cell death. Dr. Nagle’s research examines new methods to rapidly detect the presence of potentially useful anticancer agents that target specific biochemical mechanisms involved in the development and spread of tumors.
Dr. Nagle received his undergraduate training at Portland State University and Oregon State University, where he earned his B.S. in Pharmacy in 1989. He earned his Ph.D. in Pharmacy in 1994 at the Oregon State University College of Pharmacy. His graduate research detailed the chemistry and biosynthesisof marine eicosanoids and antitumor agents. Dr. Nagle worked at the University of Guam Marine Laboratory (1995-1996). He then joined the Department of Biochemistry at the University of Texas – Southwestern Medical Center at Dallas. Dr. Nagle joined the Department of Pharmacognosy in 1997. He was appointed Professor of Pharmacognosy and Research Professor of RIPS in 2009.Click to View Current Research and Publications