University of Mississippi
Dr. Babu Tekwani
Education:
  • Ph.D. Lucknow University, India
  • M.Sc. G.B. Pant University, India
Appointment(s):
  • Principal Scientist in the National Center for Natural Products Research
  • Coordinator, UM/WRAIR Discovery Program
  • Professor of Pharmacology

Interests
  • Biochemistry, Molecular Biology, Genomics of Eukaryotic Pathogens; New Drug Discovery Research. Comparative functional & structural genomics of common target pathways/enzymes of eukaryotic pathogens (Plasmodium falciparum; Leishmania donovani and Trypanosoma brucei). In vitro screening (molecular target-based and cell based assays); Development of assays and High Throughput Screening; Molecular cloning, overexpression, functional characterization and validation of potential target enzymes;
  • Molecular basis of pathogenesis of the disease caused by eukaryotic pathogens;
  • In vitro drug metabolism and drug-drug interactions.
  • Laboratory animal models of the disease (malaria & leishmaniasis) and in vivo screening.
  • New insights into to mechanism of drug induced hemolytic toxicity; In vitro assays for prediction of hemolytic toxicity potential of drugs.
  • Epigenetic mechanism of neuronal cellsí differentiation; In vitro screening of natural products for effects on neuritic outgrowth.

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