Research Projects

Project Investigators

The Center of Research Excellence in Natural Products Neuroscience (CORE-NPN) supports a formal mentoring program to promote the establishment of independent research programs for investigators. All investigators receive bridge funding ($100,000-$150,000 per year) to support their research. The investigators are required to submit a competitive R01 grant application to NIH within two years of receiving support through this program.

CORE-NPN Investigators

PROJECT 5: Delta-8-Tetrahydrocannabinol in the Management of Glaucoma

P.I.: Michael Repka, Chair and Professor, Department of Pharmaceutics and Drug Delivery, Director of Pii Center for Pharmaceutical Technology.

The purpose of this project is to investigate how THC can be used and delivered in ocular tissues and assist in the management of Glaucoma.

PROJECT 6: Fluorinated Derivatives of Anthocyanin Natural Products for Brain Neurodegeneration

P.I.: David Colby, Associate Professor, Department of BioMolecular Sciences

PROJECT 7: Intranasal Delivery of Ziconotide Using Muco-similar Vehicles

Mentor: Michael Repka, Ph.D. P.I.: S. Narasimha Murthy, Associate Professor, Department of Pharmaceutics and Drug Delivery

Small Grant Projects

The goal of Small Grant Projects is to provide a mechanism that will allow rapid transition of investigators and their approved projects as COBRE-sponsored junior investigators. Since COBRE funds cannot be carried over from year-to-year, it is important to have junior investigators and projects waiting in the wings for rapid transition into fully-funded junior investigator slots as they become available (e.g. when an existing junior investigator project is funded as an independent R01). Therefore, the CORE-NPN supports Small Grants to junior faculty who conduct research at the interface of natural products and neuroscience.

Current Small Grant Recipients:

Kristie Willett

Project: Identifying Novel Cannabinoid Analogues for the Treatment of Dravet Syndrome


P.I.: Kristine Willett
Professor, Department of BioMolecular Sciences

Joshua Sharp1

Project: In vitro Ligand Screening by Small Molecule Hydroxyl Radical Footprinting


P.I.: Joshua Sharp
Associate Professor, Department of BioMolecular Sciences