DR. PRAKASH BHAGAV received his Bachelor inPharmacy in 2002 from Rajiv Gandhi University of Health Sciences, Karnataka, India, his Masters in Pharmaceutics in (2005) from Rajiv Gandhi University of Health Sciences, Karnataka, India and his Ph.D. in Pharmaceutics in 2011 from Birla Institute of Technology and Science (BITS), Pilani, Rajasthan, India.
He worked with Piramal Healthcare Ltd (Formerly Nicholas Piramal India Ltd), Mumbai, India as Research Scientist: Formulation R & D from 2011-2012; with Panacea Biotec Ltd, Chandigarh, India as Senior Scientist: ADDR R & D for 1.5 years.
He has experience in developing Novel drug delivery systems such as CR suspensions, Extended release products for NDA filing, NCE formulations for IND filing (ophthalmic and oral), Long acting Nanocrystal Depot injections and Biosimilar products for POC and clinical trials and scaling up to commercial scale. He is also experienced in ocular formulation design, disposition and Pharmacokinetic and Pharmacodynamic evaluation in normal as well as induced animal models.
His dissertation comprised of “Design and evaluation of novel ophthalmic drug delivery systems of Brimonidine tartrate”.
The focal points of the thesis include preformulation studies, formulation development and optimization (solid ocular inserts, ophthalmic in situ gels and long acting nanoparticle formulations) and optimization, in vivo evaluation pharmacokinetic and pharmacodynamic evaluation in alpha-chymotrypsin induced glaucoma models.
Dr. Prakash’s research interests are Pharmaceutical product development, Novel drug delivery systems, formulation development for oral, ophthalmic products, preformulation and ocular pharmacokinetics.
Prakash Bhagav, Hari Om Upadhyay, Sajeev Chandran. Brimonidine TartrateñEudragit Long-Acting Nanoparticles: Formulation, Optimization, In Vitro and In Vivo Evaluation.AAPS PharmSciTechh, DOI: 10.1208/s12249-011-9675-1; Pages: 1-15
Prakash Bhagav, Darshan Shaha, Vaibhav Trivedi, Sajeev Chandran. Novel sustained release ocuserts for brimonidine tartrate for improved treatment of open angle glaucoma. Drug Delivery and Translational Research, Volume 1, Number 2, April 2011, pp. 161- 174(14)
Prakash Bhagav, Pandurang Deshpande, Saurabh Pandey, Sajeev Chandran. Development and validation of stability indicating UV spectrophotometric method for the estimation of brimonidine tartrate in pure form, formulations and preformulation Studies. Der Pharmacia Lettre, 2010, 2(3): 106-122.
Prakash Bhagav, Sajeev Chandran, Sujitha Vattikonda. 2007. Formulation and in-vitro evaluation of sustained release ophthalmic gels of rebamipide for treating dry eye syndrome; AAPS Journal, 9 (S2), 2007, Abstract M1214.
Prakash Bhagav, Durlabh Sharma, Sajeev Chandran. Novel ocular in situ gel preparations of brimonidine tartrate: formulation, optimization, in vitro and in vivo evaluation (Communicated).
Prakash Bhagav, Luv Bugga, Sajeev Chandarn. Chitosan nanoparticles of brimonidine tartrate for ocular delivery: formulation, optimization, in vitro and in vivo evaluation (communicated).